GFRA4 polyclonal, anti-human, mouse, rat

Protein Family: Receptors and Channels

Pathway and Disease: Development and Behavior, Signaling Molecules and Interaction

Description:
GDNF family receptor alpha-4 (GFRA4) is the receptor for persephin. GFRA4 mediates the GDNF-induced autophosphorylation and activation of the RET receptor. GFRA4 is important in C-cell development and in the postnatal developement of the adrenal medulla. GFRA4 is predominantly expressed in the adult thyroid gland.

Alternate Names: GDNF family receptor alpha-4, GFR-alpha-4, Persephin receptor, GFRA4

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:200-1:500

Accession No.: Q9GZZ7

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human GFRA4.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 5 mg/ml BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.