GRO alpha human active recombinant protein

GRO alpha human active recombinant protein

€295.00
In stock
SKU
600331
Catalog Number: 600331
Size: 0.025 mg
Datasheet
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Protein Family: Cytokines

Pathway and Disease: Signaling Molecules and Interaction, Immune System, Infectious Diseases

Alternate Names: GRO-alpha, GRO alpha, GROα, GRO, MGSA, CXCL1 protein, Growth-regulated alpha protein, C-X-C motif chemokine 1, Melanoma growth stimulatory activity, Neutrophil-activating protein 3, NAP-3, GRO-alpha(1-73), CINC-1Description:
Growth Regulated Protein alpha (GROalpha), also known as CXCL1, is a chemokine thought to have mitogenic properties and chemoattract neutrophils. Secreted by macrophages, epithelial cells, neutrophils and melanomas, GROalpha signals through chemokine receptor, CXCR2, and has been implicated in the processes of spinal cord formation, inflammation, angiogenesis, tumorigenesis, and wound healing. Human GRO alpha is produced in E.coli. Recombinant human GROα is a non-glycosylated protein, containing 73 amino acids, with a molecular weight of 7.9 kDa.

Source: E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.

Applications: E, WB

Application Notes:
The activity is determined by the ability to chemoattract human neutrophils at concentrations between 10-100 ng/mL. Specific activity: 1 x 10e5 units/mg

Accession No.: P09341

MW: 7900 Da

Sequence:
ASVATELRCQ CLQTLQGIHP KNIQSVNVKS PGPHCAQTEV IATLKNGRKA CLNPASPIVK KIIEKMLNSD KSN

Purity:
Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.

Format:
Each vial contains 25 ug of lyophilized protein. Reconstitute with 0.25 ml sterile deionized water for a final concentration of 0.1 mg/ml.

Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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