GSK-3b (C-term) polyclonal, anti-human, mouse, rat

Protein Family: Enzymes, Protein Kinases

Pathway and Disease: Cancers, Cell Communication, Cell Growth and Death, Development and Behavior, Endocrine System, Immune System, Neurodegenerative Disorders, Signal Transduction

Description:
GSK3b (Glycogen synthase kinase-3 beta) participates in the Wnt signaling pathway. GSK3b is implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor Jun. GSK3b phosphorylates Jun at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA.

Alternate Names: Glycogen synthase kinase-3 beta, GSK-3 beta, GSK3B

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Accession No.: P49841

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human GSK3b.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.