GST pi polyclonal, anti-human, rat
€378.00
In stock
SKU
251861
Catalog Nr.: 251861
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Protein Family: Enzymes, Epitope Tags
Pathway and Disease: Signaling Molecules and Interaction, Amino Acid Metabolism
Description:
Enzymes of the glutathione S-transferase (GST) family are composed of many cytosolic, mitochondrial and microsomal (now designated as MAPEG) proteins. GSTs are present in eukaryotes and in prokaryotes, where they catalyze a variety of reactions and accept endogenous and xenobiotic substrates. GSTs can constitute up to 10% of cytosolic protein in some mammalian organs. GSTs catalyse the conjugation of reduced glutathione, via a sulfhydryl group, to electrophilic centers on a wide variety of substrates. This activity detoxifies endogenous compounds such as peroxidised lipids as well as breakdown of xenobiotics. GSTs may also bind toxins and function as transport proteins, and, therefore, an early term for GSTs was “ligandin”. The mammalian GST super-family consists of cytosolic dimeric isoenzymes of 45–55 kDa size that have been assigned to at least six classes: Alpha, Mu, Pi, Theta, Zeta and Omega.
Alternate Names: Glutathione S-transferase P, GST class-pi, GSTP1-1, GST pi, GSTP1-1, GSTP1, FAEES3, GST3
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: P09488
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human GST pi.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Qian G et al. 2013. Sage Journals. Toxicology Pathology. doi: 10.1177/0192623313477256. PMID# 23423819.
Pathway and Disease: Signaling Molecules and Interaction, Amino Acid Metabolism
Description:
Enzymes of the glutathione S-transferase (GST) family are composed of many cytosolic, mitochondrial and microsomal (now designated as MAPEG) proteins. GSTs are present in eukaryotes and in prokaryotes, where they catalyze a variety of reactions and accept endogenous and xenobiotic substrates. GSTs can constitute up to 10% of cytosolic protein in some mammalian organs. GSTs catalyse the conjugation of reduced glutathione, via a sulfhydryl group, to electrophilic centers on a wide variety of substrates. This activity detoxifies endogenous compounds such as peroxidised lipids as well as breakdown of xenobiotics. GSTs may also bind toxins and function as transport proteins, and, therefore, an early term for GSTs was “ligandin”. The mammalian GST super-family consists of cytosolic dimeric isoenzymes of 45–55 kDa size that have been assigned to at least six classes: Alpha, Mu, Pi, Theta, Zeta and Omega.
Alternate Names: Glutathione S-transferase P, GST class-pi, GSTP1-1, GST pi, GSTP1-1, GSTP1, FAEES3, GST3
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: P09488
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human GST pi.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Qian G et al. 2013. Sage Journals. Toxicology Pathology. doi: 10.1177/0192623313477256. PMID# 23423819.
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