HCV-NS4a polyclonal, anti-virus

Protein Family: Enzymes, Peptidases

Pathway and Disease: Cancers, Cell Growth and Death, Immune System, Infectious Diseases, Lipid Metabolism, Signaling Molecules and Interaction, Transcription

Description:
Hepatitis C virus (HCV) non-structural protein 4A (NS4A) in association with NS3 is involved in the cleavage of NS3-NS4A, NS4A-NS4B, NS4B-NS5B and NS5B-NS5B. NS4A interacts with NS3 serine protease and stabilizes its folding. NS3/NS4A complex also prevents phosphorylation of human IRF3, thus preventing the establishment of dsRNA induced antiviral state.

Alternate Names: Genome polyprotein hepatitis C virus, Non-structural protein 4A, NS4A, p8

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: P26662

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of hepatitis virus C NS4A.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.