HDAC1 polyclonal, anti-human, mouse, rat

Protein Family: Enzymes

Pathway and Disease: Signal Transduction, Cancers, Neurodegenerative Disorders, Cell Growth and Death, Transcription

Description:
Histone deacetylase 1 (HDAC1) is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation plays a crucial role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC1 is sumoylated on Lys-444 and Lys-476, which promotes enzymatic activity.

Alternate Names: Histone deacetylase 1, HD1, HDAC1, RPD3L1

Application Notes: E: 1:10,000-1:50,000; WB: 1:100-1:1,000

Accession No.: Q13547

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human HDAC1.

Format: Each vial contains 0.1 mL of crude serum with 0.09% sodium azide.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.