HDAC4 (clone 7B2), anti-human
€394.00
In stock
SKU
252949
Catalog Nr.: 252949
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: WB
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: WB
Protein Family: Enzymes
Pathway and Disease: Signal Transduction, Cancers, Neurodegenerative Disorders, Cell Growth and Death, Transcription
Description:
HDAC4 (Histone deacetylase 4) is a member of the histone deacetylase family. Histones play a critical role in transcriptional regulation, cell cycle progression and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC4 belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
Alternate Names: Histone deacetylase 4, HD4, KIAA0288, HDAC4
Application Notes: WB: 1:500-1:2000
Accession No.: P56524
Antigen: Purified recombinant fragment of human HDAC4 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Signal Transduction, Cancers, Neurodegenerative Disorders, Cell Growth and Death, Transcription
Description:
HDAC4 (Histone deacetylase 4) is a member of the histone deacetylase family. Histones play a critical role in transcriptional regulation, cell cycle progression and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC4 belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
Alternate Names: Histone deacetylase 4, HD4, KIAA0288, HDAC4
Application Notes: WB: 1:500-1:2000
Accession No.: P56524
Antigen: Purified recombinant fragment of human HDAC4 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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