Hemoglobin alpha polyclonal, anti-human, mouse, rat, bovine, chicken
€378.00
In stock
SKU
251337
Catalog Nr.: 251337
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Protein Family: Transporters
Pathway and Disease: Membrane Transport
Description:
Hemoglobin alpha is involved in oxygen transport from the lung to the various peripheral tissues. Defects in hemoglobin alpha are the cause of alpha-thalassemia (A-THAL). The thalassemias are the most common monogenic diseases and occur mostly in Mediterranean and Southeast Asian populations. The hallmark of alpha-thalassemia is an imbalance in globin-chain production in the adult HbA molecule. The level of alpha chain production can range from none to very nearly normal levels. Untreated, most patients die in childhood or early adolescence.
Alternate Names: HBA1, Hemoglobin alpha, Hemoglobin alpha 1, Hemoglobin subunit alpha, Hemoglobin alpha chain, Alpha-globin, HBA1
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: P69905
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human hemoglobin alpha.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Membrane Transport
Description:
Hemoglobin alpha is involved in oxygen transport from the lung to the various peripheral tissues. Defects in hemoglobin alpha are the cause of alpha-thalassemia (A-THAL). The thalassemias are the most common monogenic diseases and occur mostly in Mediterranean and Southeast Asian populations. The hallmark of alpha-thalassemia is an imbalance in globin-chain production in the adult HbA molecule. The level of alpha chain production can range from none to very nearly normal levels. Untreated, most patients die in childhood or early adolescence.
Alternate Names: HBA1, Hemoglobin alpha, Hemoglobin alpha 1, Hemoglobin subunit alpha, Hemoglobin alpha chain, Alpha-globin, HBA1
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: P69905
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human hemoglobin alpha.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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