HER2 Phospho (pY877) [clone EP123], anti-human

Description: HER2 / ErbB2 is one of four members of the ErbB receptor family of transmembrane receptor-like tyrosine kinases .The kinase activity of ErbB2 can be activated without a ligand if it is overexpressed, and by association with other ErbB proteins. HER2 is overexpressed in 25–30% of all breast cancers, including primary as well as metastatic breast tumors. HER2 has been widely investigated as a prognostic indicator. Detection of phosphorylated HER2 may aid in predicting breast cancer progression. Localization: membraneDilution: 50-200Positive Control: breast caHIER: EDTA pH8.0Status: RUO