HER3 (C-ERB-3) [clone SP71], anti-human

Description: The gene for c-erbB-3/HER-3 is located on the long arm of human chromosome 12 (12q13) and is transcribed into a 6.2kb mRNA which is translated into a 160/180kDa glycoprotein. The c-erbB-3/HER-3 gene encodes secreted as well as transmembrane receptor tyrosine kinase due to alternative splicing. The c-erbB-3 is overexpressed in a variety of tumors including breast, stomach, pancreas, and colon.Localization: membraneDilution: 25-50Positive Control: small IntestineHIER: citrate pH6.0 or EDTA pH8.0Status: RUO