HIRA Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP17007a
Background:
This gene encodes a histone chaperone that preferentiallyplaces the variant histone H3.3 in nucleosomes. Orthologs of thisgene in yeast, flies, and plants are necessary for the formation oftranscriptionally silent heterochomatin. This gene plays animportant role in the formation of the senescence-associatedheterochromatin foci. These foci likely mediate the irreversiblecell cycle changes that occur in senescent cells. It is consideredthe primary candidate gene in some haploinsufficiency syndromessuch as DiGeorge syndrome, and insufficient production of the genemay disrupt normal embryonic development.
Other Names:
Protein HIRA, TUP1-like enhancer of split protein 1, HIRA, DGCR1, HIR, TUPLE1
Gene Name: HIRA
Gene ID: 7290
Primary Accession: P54198
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a histone chaperone that preferentiallyplaces the variant histone H3.3 in nucleosomes. Orthologs of thisgene in yeast, flies, and plants are necessary for the formation oftranscriptionally silent heterochomatin. This gene plays animportant role in the formation of the senescence-associatedheterochromatin foci. These foci likely mediate the irreversiblecell cycle changes that occur in senescent cells. It is consideredthe primary candidate gene in some haploinsufficiency syndromessuch as DiGeorge syndrome, and insufficient production of the genemay disrupt normal embryonic development.
Other Names:
Protein HIRA, TUP1-like enhancer of split protein 1, HIRA, DGCR1, HIR, TUPLE1
Gene Name: HIRA
Gene ID: 7290
Primary Accession: P54198
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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