HIST1H2BN Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP13115a
Background:
Histones are basic nuclear proteins that are responsiblefor the nucleosome structure of the chromosomal fiber ineukaryotes. Two molecules of each of the four core histones (H2A,H2B, H3, and H4) form an octamer, around which approximately 146 bpof DNA is wrapped in repeating units, called nucleosomes. Thelinker histone, H1, interacts with linker DNA between nucleosomesand functions in the compaction of chromatin into higher orderstructures. This gene is intronless and encodes a member of thehistone H2B family. Transcripts from this gene lack polyA tails butinstead contain a palindromic termination element. This gene isfound in the small histone gene cluster on chromosome 6p22-p21.3.
Other Names:
Histone H2B type 1-N, Histone H2Bd, H2B/d, HIST1H2BN, H2BFD
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13115a was selected from the N-term region of HIST1H2BN. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: H2BC15 (HGNC:4749)
Gene ID: 8341
Primary Accession: Q99877
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Histones are basic nuclear proteins that are responsiblefor the nucleosome structure of the chromosomal fiber ineukaryotes. Two molecules of each of the four core histones (H2A,H2B, H3, and H4) form an octamer, around which approximately 146 bpof DNA is wrapped in repeating units, called nucleosomes. Thelinker histone, H1, interacts with linker DNA between nucleosomesand functions in the compaction of chromatin into higher orderstructures. This gene is intronless and encodes a member of thehistone H2B family. Transcripts from this gene lack polyA tails butinstead contain a palindromic termination element. This gene isfound in the small histone gene cluster on chromosome 6p22-p21.3.
Other Names:
Histone H2B type 1-N, Histone H2Bd, H2B/d, HIST1H2BN, H2BFD
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13115a was selected from the N-term region of HIST1H2BN. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: H2BC15 (HGNC:4749)
Gene ID: 8341
Primary Accession: Q99877
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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