Histone H2B (mono methyl R79) polyclonal, anti-human, mouse
€428.00
In stock
SKU
BS94094
Catalog Number: BS94094
Size: 100 µl
Other Size: 50 µl
Isotype: rabbit IgG
Applications: WB, ICC/IF, IHC
Questions? Contact us!
Size: 100 µl
Other Size: 50 µl
Isotype: rabbit IgG
Applications: WB, ICC/IF, IHC
Questions? Contact us!
Background:
Eukaryotic histones are basic and water soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer, formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene, that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.
Alternative Name:
Hist2h2be, H2B 1A, H2B, H2B histone family, H2B2f, H2B2F, H2Ba, H2Bf, HIST2H2BF, histone H2B, histone H2B type 1, Histone H2B type 2-F, MGC131639,
Application Dilution:
WB:1:1,000
ICC:1:50-1:200
IHC:1:50-1:200
Specificity: Histone H2B (mono methyl R79) polyclonal antibody detects endogenous levels of Histone H2B protein only when mono-methylated at R79.
Immunogen:
recombinant protein
MW: 14 kDa
Swiss-Prot: O60814(Human) P06899(Human) P23527(Human) P33778(Human) Q64524(Mouse)
Purification & Purity:
ProA affinity purified
Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
For research use only, not for use in diagnostic procedure.
Eukaryotic histones are basic and water soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer, formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene, that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.
Alternative Name:
Hist2h2be, H2B 1A, H2B, H2B histone family, H2B2f, H2B2F, H2Ba, H2Bf, HIST2H2BF, histone H2B, histone H2B type 1, Histone H2B type 2-F, MGC131639,
Application Dilution:
WB:1:1,000
ICC:1:50-1:200
IHC:1:50-1:200
Specificity: Histone H2B (mono methyl R79) polyclonal antibody detects endogenous levels of Histone H2B protein only when mono-methylated at R79.
Immunogen:
recombinant protein
MW: 14 kDa
Swiss-Prot: O60814(Human) P06899(Human) P23527(Human) P33778(Human) Q64524(Mouse)
Purification & Purity:
ProA affinity purified
Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
For research use only, not for use in diagnostic procedure.
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