Histone H3 (acetyl K14) polyclonal, anti-human, mouse, rat

Background:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Alternative Name:
HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, HIST1H3F, H3FI, HIST1H3G, H3FH, HIST1H3H, H3FK, HIST1H3I, H3FF, HIST1H3J, H3FJ,

Application Dilution:
WB:1:500-1:2,000
ICC:1:200-1:1,000
IHC:1:50-1:200
IP:1:10-1:50

Specificity: Histone H3 (acetyl K14) polyclonal antibody detects endogenous levels of Histone H3 protein only when acetylated at K14.

Immunogen:
Recombinant protein

MW: 11/15 kDa

Swiss-Prot: P68431(Human) P68433(Mouse) Q6LED0(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.