Histone H3A polyclonal, anti-humna, mouse, rat, bovine chicken, hamster, drosophila, rabbit, pig, palnt, xenopus, zebrafish, other
€378.00
In stock
SKU
250690
Catalog Nr.: 250690
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Protein Family: Chaperones and Folding Catalysts, Ribosomes
Pathway and Disease: Cancers, Cell Growth and Death, Replication and Repair, Transcription
Description:
Histones are the core components of the nucleosomes that wrap and compact DNA into chromatin. DNA compacting limits accessibility to the cellular machineries which require DNA as template. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. The accessibility of DNA is regulated by post-translational modifications of histones such as acetylation, methylation and phosphorylation. The nucleosome is a histone octamer containing two molecules each of histone proteins H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
Alternate Names: Histone H3.1, H3/a, HIST1H3A, H3FA
Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500
Accession No.: P68431
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human H3A.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Cancers, Cell Growth and Death, Replication and Repair, Transcription
Description:
Histones are the core components of the nucleosomes that wrap and compact DNA into chromatin. DNA compacting limits accessibility to the cellular machineries which require DNA as template. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. The accessibility of DNA is regulated by post-translational modifications of histones such as acetylation, methylation and phosphorylation. The nucleosome is a histone octamer containing two molecules each of histone proteins H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
Alternate Names: Histone H3.1, H3/a, HIST1H3A, H3FA
Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500
Accession No.: P68431
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human H3A.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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