HLA-DR polyclonal, anti-human

Protein Family: Transporters; CAM Ligands; Cell Adhesion Molecules; Cellular Antigens

Pathway and Disease: Signaling Molecules and Interaction; Immune System; Infectious Diseases; Metabolic Disorders

Description:
HLA class II histocompatibility antigen (HLA-DR) binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by CD4 T-cells. HLA-DR is a heterodimer of an alpha and a beta subunit; also referred as MHC class II molecule. The peptides presented by HLA-DR and other MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases.

Alternate Names: HLA class II histocompatibility antigen, DRB1-13 beta chain, MHC class II antigen DRB1-13, HLA-DRB1, DR-13, DR alpha chain, MHC class II antigen DRA, HLA-DRA, HLA-DRA1, HLADR

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: P01903

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human HLA-DR.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.