HMGA1 polyclonal, anti-human, mouse, rat, bovine, chicken

Protein Family: Transcription Factors

Pathway and Disease: Transcription

Description:
High mobility group AT-hook protein 1 (HMGA1) binds preferentially to the minor groove of A+T rich regions in double stranded DNA. HMGA1 is involved in nucleosome phasing and in the 3'-end processing of mRNA transcripts. HMGA1 is also involved in the transcriptional regulation of genes containing, or in close proximity, to A+T-rich regions. A chromosomal aberration involving HMGA1 is found in pulmonary chondroid hamartoma.

Alternate Names: HMGA1, High mobility group AT-hook protein 1, High mobility group protein HMG-I/HMG-Y, HMG-I(Y), High mobility group protein A1, High mobility group protein R, HMGIY

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IP: 1:100-1:500

Accession No.: P17096

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of HMGA1.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.