HNF-4α/γ (Acetyl Lys127/79) Polyclonal Antibody

Background:
hepatocyte nuclear factor 4 alpha(HNF4A) Homo sapiens The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012],

Alternative Names:
Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Nuclear receptor subfamily 2 group A member 1) (Transcription factor 14) Hepatocyte nuclear factor 4-gamma (HNF-4-gamma) (Nuclear receptor subfamily 2

Immunogen: Synthetic Acetyl peptide from human protein at AA range: 127(HNF-4α)/79(HNF-4γ)

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 55

GeneID: HNF4A HNF4 NR2A1 TCF14 HNF4G NR2A2

Storage: -20°C/1 year

NOTE: For Research Use Only