HPV 16 E6 (clone 13E2), anti-human

Source:
A BALB/c mouse was immunized with HPV-16 E6 synthetic peptide.
Fusion partner: X63-Ag8-653.

Specifications:
Monoclonal antibody HPV-13E2 reacts with HPV-16 E6 peptide (MHQKRTAMFQDPPQERPRKLPQLC). Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies.

Species reactivity:
Positive: human.

Applications:
Identification of HPV-16 E6.
ELISA: +
Frozen sections: +
Paraffin sections: -

Positive control: HPV 16 E6 synthetic peptide or recombinant protein.

References:
- Beldermann, Frank: Entwicklung monoklonaler Antikörper gegen das frühe Virusprotein E6 des humanen Papillomavirus HPV-16, Thesis, University of Heidelberg, Germany (1995)