Human IgA secretory component (clone SC-05), anti-human, rat

Source:
A BALB/c mouse was immunized with affinity purified human secretory component.
Fusion partner: P3-X63-Ag8.653.

Specifications:
SC-05 reacts with a reduction resistant epitope on 80 kDa human secretory component (both free and bound to SIgA). Secretory component is differentially expressed in epithelium, thus SC-05 can identify subpopulations of epithelial cells and epithelial differentiation. Secretory component negative cell lines are not stained with SC-05.

Species reactivity:
Positive: human, rat.

Applications:
SC-05 is useful for studying the distribution and level of both free and bound secretory component and to identify epithelial differentiation in relevant tissues.
ELISA: +
Flow cytometry: +
Frozen sections: +
Immuno-precipitation: +
Paraffin sections: Citrate
Western blot: +

Positive control: Stomach, lung, or breast tumor.

References:
- Kvale, D. et al, Int J Cancer 42(4): 638-641 (1988).
- Bartek, J. et al, Histochem91(3): 235-244 (1989).
- Bartek, J. et al, Histochem J22(10): 537-534 (1990).