Human OX40 Protein, hFc-His tag
€403.00
In stock
SKU
PME100022
Description: Recombinant human OX40 protein with C-terminal human Fc and 6×His tag
Background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
Synonyms: TNFRSF4, OX40, CD134, OX40L receptor, ACT35, TXGP1L
Molecular Weight: The protein has a predicted molecular mass of 47.2 kDa after removal of the signal peptide.
Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Buffer: PBS, pH7.4
Buffer: Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage: Research use only
Background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
Synonyms: TNFRSF4, OX40, CD134, OX40L receptor, ACT35, TXGP1L
Molecular Weight: The protein has a predicted molecular mass of 47.2 kDa after removal of the signal peptide.
Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Buffer: PBS, pH7.4
Buffer: Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage: Research use only
| Is Featured? | No |
|---|
Write Your Own Review