Human TIM3 Protein, mFc-His Tag
€443.00
In stock
SKU
PME100030
Description: Recombinant human TIM3 protein with C-terminal mouse Fc and 6×His tag
Background:
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
Synonyms: HAVCR2, TIM3, TIMD3, FLJ14428, KIM3
Molecular Weight: The protein has a predicted molecular mass of 47.5 kDa after removal of the signal peptide.
Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Buffer: PBS, pH7.4
Buffer: Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage: Research use only
Background:
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
Synonyms: HAVCR2, TIM3, TIMD3, FLJ14428, KIM3
Molecular Weight: The protein has a predicted molecular mass of 47.5 kDa after removal of the signal peptide.
Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Buffer: PBS, pH7.4
Buffer: Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage: Research use only
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