HumanInterleukin-4, IL-4 HiLA ELISA Kit

Introduction:
The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. Upon activation by IL-4, Th2 cells subsequently produce additional IL-4 in a positive feedback loop. IL-4 is produced primarily by mast cells, Th2 cells, eosinophils and basophils.It is closely related and has functions similar to IL-13.Interleukin 4 has many biological roles, including the stimulation of activated B cell and T cell proliferation, and the differentiation of B cells into plasma cells. It is a key regulator in humoral and adaptive immunity. IL-4 induces B cell class switching to IgE, and up-regulates MHC class II production. IL-4 decreases the production of Th1 cells, macrophages, IFN��, and dendritic cells IL-12.

Application
For quantitative detection of human IL-4 in buffer solution, serum, cell culture supernatant.

Storage Conditions
Store at 2-8 C in dark for 12 months.