ICAD polyclonal, anti-human

Protein Family: Enzymes

Pathway and Disease: Signaling Molecules and Interaction, Cell Growth and Death

Description:
Inhibitor of CAD (ICAD) is an inhibitor of the caspase-activated DNase (DFF40). ICAD is a heterodimer of DFFA and DFFB. ICAD is phosphorylated upon DNA damage, probably by ATM or ATR.

Alternate Names: ICAD, Inhibitor of Caspase-Activated Dnase, DNA fragmentation factor subunit alpha, DNA fragmentation factor 45 kDa subunit, DFF-45, Inhibitor of CAD, DFFA, DFF1, DFF45

Application Notes: E: 1:40,000-1:80,000; WB: 1:200-1:1,000

Accession No.: O00273

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human ICAD.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.