IFNa-2a human active recombinant protein

IFNa-2a human active recombinant protein

€295.00
In stock
SKU
600346
Catalog Number: 600346
Size: 0.1 mg
Datasheet
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Protein Family: Cytokines

Pathway and Disease: Folding, Sorting and Degradation; Signaling Molecules and Interaction; Immune System

Alternate Names: IFN-alpha 2a, Interferon alpha-2, Interferon alpha-A, LeIF A, IFNA2Description:
Interferon-alpha 2a (IFN alpha 2a) is a Type I interferon made by leukocytes during viral infection. It has anti-viral and non-proliferative activity induced by JAK1-STAT signaling. IFN-alpha 2s are the most widely used type for therapeutic purposes. IFN alpha 2b is a variant of IFN alpha 2a that differs by one amino acid. Human IFNa-2a is produced in E. coli. Recombinant human IFN alpha 2a is a non-glycosylated protein, containing 166 amino acids, with a molecular weight of 19.37 kDa.

Source: E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.

Applications: E, WB

Application Notes:
The activity can be determined by the ability to induce antiviral activity. There is no biological assay data available at this time.

Accession No.: P01563

MW: 19370 Da

Sequence:
MCDLPQTHSL GSRRTLMLLA QMRKISLFSC LKDRHDFGFP QEEFGNQFQK AETIPVLHEM IQQIFNLFST KDSSAAWDET LLDKFYTELY QQLNDLEACV IQGVGVTETP LMKEDSILAV RKYFQRITLY LKEKKYSPCA WEVVRAEIMR SFSLSTNLQE SLRSKE

Purity:
Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.

Format:
Each vial contains 100 ug of lyophilized protein. Reconstitute with 1 ml sterile deionized water for a final concentration of 0.1 mg/ml.

Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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