IgA polyclonal, anti-rat

Protein Family: Cellular Antigens

Pathway and Disease: Immune System

Description:
IgA (immunoglobulin A) is a 160 kDa glycosylated protein produced as a monomer or as a J chain-linked dimer. Secretory IgA (sIgA) are composed of 2-4 IgA monomers linked by the J chain (15 kDa) and a secretory component (70 kDa). Monomeric IgA constitutes 5-15% of the serum immunoglobulins whereas dimeric IgA is localized to mucosa surfaces such as saliva, gastrointestinal secretion, bronchial fluids and milk. Mucosal IgA plays a major role in host defence by neutralising infectious agents at mucosal surfaces.

Alternate Names: Immunoglobulin A, type a heavy chain, IgA, secretory IgA, sIgA

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Antigen: rat IgA

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.1 mg/ml BSA, 50% glycerol with 0.09% sodium azide. Antibody was purified by Protein-A and antigen-affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.