IGF2BP3 polyclonal, anti-human, mouse, rat, dog, horse

Protein Family: Translation Factors, Transcription Factors

Pathway and Disease: Transcription, Translation

Description:
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) is an RNA-binding protein that regulates mRNA translation and stability. IGF2BP3 binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNA, and binds to sequences in the 3'-UTR of CD44 mRNA.

Alternate Names: IGF2BP3, Insulin-like growth factor 2 mRNA-binding protein 3, IGF2 mRNA-binding protein 3, IMP-3, IGF-II mRNA- binding protein 3, KH domain-containing protein overexpressed in cancer, hKOC, VICKZ family member 3, IMP3, KOC1, VICKZ3

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: O00425

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human IGF2BP3.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.5 % BSA with 0.09% sodium azide. Antibody was purified by immunogen-affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.