IgG4 (clone ), anti-human
€428.00
In stock
SKU
BS9949M
Background:
The regions of relatively constant sequence beyond the variable regions of immunoglobulins are termed constant regions (C regions) and are present in both the heavy and light chains. With very few exceptions, the sites of attachment for carbohydrates on immunoglobulins are located in these C regions. These regions also function to hold the variable regions together by using the disulfide bond between them. The C regions facilitate interaction with the antigen by increasing the maximum rotation of the immunoglobulin arms. Several studies have shown that a large population of patients with recurrent respiratory tract infection have low IgG4 concentrations.
Alternative Name:
Ig gamma-4 chain C region, IGHG4
Application Dilution: WB: 1:1000-1:5000, IHC: 1:50-1:200
Specificity: This antibody detects endogenous levels of IgG4 and does not cross-react with related proteins.
Immunogen:
Recombinant antibody.
MW: ~ 36 kDa
Swis Prot.: P01861
Purification & Purity:
Protein A affinity purified
Format:
Recombinant Rabbit Monoclonal Antibody. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The regions of relatively constant sequence beyond the variable regions of immunoglobulins are termed constant regions (C regions) and are present in both the heavy and light chains. With very few exceptions, the sites of attachment for carbohydrates on immunoglobulins are located in these C regions. These regions also function to hold the variable regions together by using the disulfide bond between them. The C regions facilitate interaction with the antigen by increasing the maximum rotation of the immunoglobulin arms. Several studies have shown that a large population of patients with recurrent respiratory tract infection have low IgG4 concentrations.
Alternative Name:
Ig gamma-4 chain C region, IGHG4
Application Dilution: WB: 1:1000-1:5000, IHC: 1:50-1:200
Specificity: This antibody detects endogenous levels of IgG4 and does not cross-react with related proteins.
Immunogen:
Recombinant antibody.
MW: ~ 36 kDa
Swis Prot.: P01861
Purification & Purity:
Protein A affinity purified
Format:
Recombinant Rabbit Monoclonal Antibody. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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