IHOG (clone 3G8), anti-drosophila
€394.00
In stock
SKU
253017
Catalog Nr.: 253017
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: WB
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: WB
Protein Family: Proteoglycans
Pathway and Disease: Signal Transduction, Cell Growth and Death
Description:
IHOG (Interference hedgehog) is a type 1 membrane protein mediates response to the active Hedgehog (Hh) protein signal. Ihog mutations produce defects characteristic of Hh signaling loss in embryos and imaginal discs, and epistasis analysis places ihog action at or upstream of the negatively acting receptor component, Patched (Ptc). The first of two extracellular fibronectin type III (FNIII) domains of the Ihog protein mediates a specific interaction with Hh protein in vitro, but the second FNIII domain is additionally required for in vivo signaling activity and for Ihog-enhanced binding of Hh protein to cells coexpressing Ptc.
Alternate Names: CG9211, CT26314, Dmel\CG9211, ihog, Ihog, Interference hedgehog
Application Notes: WB: 1:200-1:1000
Accession No.: Q9VM64
Antigen: Purified recombinant fragment of human IHOG expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Signal Transduction, Cell Growth and Death
Description:
IHOG (Interference hedgehog) is a type 1 membrane protein mediates response to the active Hedgehog (Hh) protein signal. Ihog mutations produce defects characteristic of Hh signaling loss in embryos and imaginal discs, and epistasis analysis places ihog action at or upstream of the negatively acting receptor component, Patched (Ptc). The first of two extracellular fibronectin type III (FNIII) domains of the Ihog protein mediates a specific interaction with Hh protein in vitro, but the second FNIII domain is additionally required for in vivo signaling activity and for Ihog-enhanced binding of Hh protein to cells coexpressing Ptc.
Alternate Names: CG9211, CT26314, Dmel\CG9211, ihog, Ihog, Interference hedgehog
Application Notes: WB: 1:200-1:1000
Accession No.: Q9VM64
Antigen: Purified recombinant fragment of human IHOG expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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