IL-1 alpha polyclonal, anti-human, mouse, rat, pig, bovine, dog, sheep
€362.00
In stock
SKU
250715
Catalog Nr.: 250715
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Protein Family: Cytokines
Pathway and Disease: Cell Growth and Death, Immune System, Metabolic Disorders, Neurodegenerative Disorders, Signal Transduction, Signaling Molecules and Interaction
Description:
Interleukin-1 (IL-1) is a cytokine produced by activated macrophages. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 is involved in the inflammatory response as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. IL-1 alpha and IL-1 beta bind to the same cell surface receptor with similar signaling responses.
Alternate Names: Interleukin-1 alpha, IL-1 alpha, Hematopoietin-1, IL1A, IL1F1
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: P01583
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human IL-1 alpha.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Pajer K et al. 2015. Exp Neurol. 269: 188-201. PMID 25889458.
Pathway and Disease: Cell Growth and Death, Immune System, Metabolic Disorders, Neurodegenerative Disorders, Signal Transduction, Signaling Molecules and Interaction
Description:
Interleukin-1 (IL-1) is a cytokine produced by activated macrophages. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 is involved in the inflammatory response as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. IL-1 alpha and IL-1 beta bind to the same cell surface receptor with similar signaling responses.
Alternate Names: Interleukin-1 alpha, IL-1 alpha, Hematopoietin-1, IL1A, IL1F1
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: P01583
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human IL-1 alpha.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Pajer K et al. 2015. Exp Neurol. 269: 188-201. PMID 25889458.
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