IL-10 polyclonal, anti-human, mouse, rat, pig, bovine, rabbit, dog
€378.00
In stock
SKU
250713
Catalog Nr.: 250713
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Protein Family: Cytokines
Pathway and Disease: Immune System, Signal Transduction, Signaling Molecules and Interaction
Description:
Interleukin 10 (IL-10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. IL-10 has pleiotropic effects in immunoregulation and inflammation such as inhibiting synthesis of IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and helper T-cells. Defects in IL-10 are a cause of susceptibility to Crohn disease, an inflammatory bowel disease.
Alternate Names: Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, IL10
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:200-1:500
Accession No.: P22301
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human IL-10.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
[1]Pova TF et al. 2016. PLoS One. 11(12):e0168973. doi:10.1371/journal.pone.0168973. eCollection2016. PMID# 28006034.
[2] Jammal MP et al. 2016. Clin Med Insights Oncol. 10:71-6. PMID#27512342
[3] TTY Han et al. 2015. Biomaterials. 72:125-37. PMID#26360790
[2] Gennaro G. et al. 2015. PLoS One. 10(8). PMID: 26270535.
[4] Jammal MP et al. 2015. Oncol lett. PMID#25624918.
[5] Dange RB et al. 2015. J Neuroinflammation. 12(1):242. PMID#25879545.
[6] Tillet S et al. 2014. Br J Surg. PMID#2540233.
[7]Meadows DN et al. 2014. Hum Mutat. doi: 10.1002/humu.22533. PMID# 24616178.
[8] Bennett L et al. 2013. PLoS ONE. 8(10):e76362. PMID# 24204618.
[9] Agarwal D et al. 2013.British Journal of Pharmacology. doi:10.1111/boh.12177. PMID# 23516971
[10] Mikael L et al. 2012. Molecular Nutrition and Food Research. doi: 10.1002/mnfr.201200152. PMID# 23112124.
[11] Li Y et al. 2012. Arterisclerosis, Thrombosis, and Vascular Biology. Atherosclerosis. 32(7): 1662-1674. PMID# 22556333.
[12] Mikael L et al. 2012. The Journal of Nutrition. 142(3): 411-418. PMID# 22259189.
Pathway and Disease: Immune System, Signal Transduction, Signaling Molecules and Interaction
Description:
Interleukin 10 (IL-10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. IL-10 has pleiotropic effects in immunoregulation and inflammation such as inhibiting synthesis of IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and helper T-cells. Defects in IL-10 are a cause of susceptibility to Crohn disease, an inflammatory bowel disease.
Alternate Names: Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, IL10
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:200-1:500
Accession No.: P22301
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human IL-10.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
[1]Pova TF et al. 2016. PLoS One. 11(12):e0168973. doi:10.1371/journal.pone.0168973. eCollection2016. PMID# 28006034.
[2] Jammal MP et al. 2016. Clin Med Insights Oncol. 10:71-6. PMID#27512342
[3] TTY Han et al. 2015. Biomaterials. 72:125-37. PMID#26360790
[2] Gennaro G. et al. 2015. PLoS One. 10(8). PMID: 26270535.
[4] Jammal MP et al. 2015. Oncol lett. PMID#25624918.
[5] Dange RB et al. 2015. J Neuroinflammation. 12(1):242. PMID#25879545.
[6] Tillet S et al. 2014. Br J Surg. PMID#2540233.
[7]Meadows DN et al. 2014. Hum Mutat. doi: 10.1002/humu.22533. PMID# 24616178.
[8] Bennett L et al. 2013. PLoS ONE. 8(10):e76362. PMID# 24204618.
[9] Agarwal D et al. 2013.British Journal of Pharmacology. doi:10.1111/boh.12177. PMID# 23516971
[10] Mikael L et al. 2012. Molecular Nutrition and Food Research. doi: 10.1002/mnfr.201200152. PMID# 23112124.
[11] Li Y et al. 2012. Arterisclerosis, Thrombosis, and Vascular Biology. Atherosclerosis. 32(7): 1662-1674. PMID# 22556333.
[12] Mikael L et al. 2012. The Journal of Nutrition. 142(3): 411-418. PMID# 22259189.
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