IL-21 human GMP recombinant protein

Backgroud: IL-21 induces the production of IgG1 and IgG3 in B-cells. IL-21 may promote the transition between innate and adaptive immunity. IL-21 may have a role in proliferation and maturation of natural killer cells in synergy with IL15. IL-21 stimulates interferon gamma production in T-cells and natural killer cells by synergy with IL15 and IL18. Dysregulation of IL-21 has a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases.

Synonyms: Interleukin-21; IL-21; Za11; IL21

Construction: Recombinant Human IL-21 is produced by our Mammalian cell expression system and the target gene encoding His25-Ser162 is expressed.

Purity: Greater than 95% as determined by reducing SDS-PAGE

Endotoxin: ≤10 EU/mg

Activity: The ED50 for this effect is ≤ 8 ng/mL

Accession No.: Q9HBE4

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.