IL-4 polyclonal, anti-mouse, rat
€378.00
In stock
SKU
251223
Catalog Nr.: 251223
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Protein Family: Cytokines
Pathway and Disease: Signaling Molecules and Interaction, Immune System, Signal Transduction, Infectious Diseases
Description:
Interleukin 4 (IL-4) is a cytokine involved in B-cell activation processes. IL-4 induces the expression of class II MHC molecules on resting B-cells. IL-4 also enhances both secretion and cell surface expression of IgE and IgG1, and regulates the expression of the low-affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Genetic variations in the IL-4 gene have been implicated in the cause of ischemic stroke.
Alternate Names: IL-4, Interleukin-4, IL4, B-cell stimulatory factor 1, BSF-1, Lymphocyte stimulatory factor 1, Binetrakin, Pitrakinra
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: P05112
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human IL-4.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction, Immune System, Signal Transduction, Infectious Diseases
Description:
Interleukin 4 (IL-4) is a cytokine involved in B-cell activation processes. IL-4 induces the expression of class II MHC molecules on resting B-cells. IL-4 also enhances both secretion and cell surface expression of IgE and IgG1, and regulates the expression of the low-affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Genetic variations in the IL-4 gene have been implicated in the cause of ischemic stroke.
Alternate Names: IL-4, Interleukin-4, IL4, B-cell stimulatory factor 1, BSF-1, Lymphocyte stimulatory factor 1, Binetrakin, Pitrakinra
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: P05112
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human IL-4.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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