IL-8 human active recombinant protein
€295.00
In stock
SKU
600326
Protein Family: Cytokines
Pathway and Disease: Cancers, Signaling Molecules and Interaction, Immune System, Infectious Diseases
Alternate Names: CXCL8, neutrophil chemotactic factorDescription:
Interleukin 8 (IL-8 or CXCL8) is an inflammatory chemokine of the CXC family that can be produced by a variety of cells but is predominantly studied in the context of macrophages and epithelial cells. IL-8 is a ligand for GPCRs, CXCR1 and CXCR2, and acts to recruit innate immune cells as well as induce phagocytosis. IL-8 is also able to induce angiogenesis. Human IL-8 is produced in E.coli. Recombinant human IL-8 is a non-glycosylated protein, containing 77 amino acids, with a molecular weight of 8.9 kDa.
Source: E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.
Applications: E, WB
Application Notes:
The activity can be determined by its ability to induce chemotaxis of primary human neutrophils at 100 ng/mL. There is no biological assay data available at this time. Specific activity: 1 x 10e4 units/mg
Accession No.: P10145
MW: 8900 Da
Sequence:
AVLPRSAKEL RCQCIKTYSK PFHPKFIKEL RVIESGPHCA NTEIIVKLSD GRELCLDPKE NWVQRVVEKF LKRAENS
Purity:
Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Format:
Each vial contains 25 ug of lyophilized protein. Reconstitute with 0.25 ml sterile deionized water for a final concentration of 0.1 mg/ml.
Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
Pathway and Disease: Cancers, Signaling Molecules and Interaction, Immune System, Infectious Diseases
Alternate Names: CXCL8, neutrophil chemotactic factorDescription:
Interleukin 8 (IL-8 or CXCL8) is an inflammatory chemokine of the CXC family that can be produced by a variety of cells but is predominantly studied in the context of macrophages and epithelial cells. IL-8 is a ligand for GPCRs, CXCR1 and CXCR2, and acts to recruit innate immune cells as well as induce phagocytosis. IL-8 is also able to induce angiogenesis. Human IL-8 is produced in E.coli. Recombinant human IL-8 is a non-glycosylated protein, containing 77 amino acids, with a molecular weight of 8.9 kDa.
Source: E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.
Applications: E, WB
Application Notes:
The activity can be determined by its ability to induce chemotaxis of primary human neutrophils at 100 ng/mL. There is no biological assay data available at this time. Specific activity: 1 x 10e4 units/mg
Accession No.: P10145
MW: 8900 Da
Sequence:
AVLPRSAKEL RCQCIKTYSK PFHPKFIKEL RVIESGPHCA NTEIIVKLSD GRELCLDPKE NWVQRVVEKF LKRAENS
Purity:
Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Format:
Each vial contains 25 ug of lyophilized protein. Reconstitute with 0.25 ml sterile deionized water for a final concentration of 0.1 mg/ml.
Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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