IL1 Receptor Antagonist (clone KT6), anti-human
€354.00
In stock
SKU
250102
Catalog Nr.: 250102
Size: 0.1 mg
Isotype: mouse IgG1
Applications: E, WB
Size: 0.1 mg
Isotype: mouse IgG1
Applications: E, WB
Protein Family: Cytokines
Pathway and Disease: Immune System, Signaling Molecules and Interaction
Description:
The interleukin-1 receptor antagonist (IL-1ra) inhibits the activity of IL-1 by binding to the IL-1 receptor but has no IL-1 like activity. IL-1ra has 4 isoforms produced by alternative splicing, only isoform 1 is secreted. The intracellular forms of IL-1ra are predominantly expressed in epithelial cells. Under the name Kineret (Amgen), IL-1ra is used to treat patients with moderate to severe case of active rheumatoid arthritis by slowing the progression of the structural damages. This antibody recognizes human IL-1ra in ELISA.
Alternate Names: Interleukin-1 receptor antagonist protein, IL-1ra, IRAP, IL1 inhibitor, IL-1RN, ICIL-1RA, Anakinra, IL1RN, IL1F3, IL1RA
Application Notes: E: 1 mg/ml; WB: 1:100-1:1,000
Accession No.: P18510, NP_776214
Antigen: Recombinant human IL1 receptor antagonist protein
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.1% gelatin with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Immune System, Signaling Molecules and Interaction
Description:
The interleukin-1 receptor antagonist (IL-1ra) inhibits the activity of IL-1 by binding to the IL-1 receptor but has no IL-1 like activity. IL-1ra has 4 isoforms produced by alternative splicing, only isoform 1 is secreted. The intracellular forms of IL-1ra are predominantly expressed in epithelial cells. Under the name Kineret (Amgen), IL-1ra is used to treat patients with moderate to severe case of active rheumatoid arthritis by slowing the progression of the structural damages. This antibody recognizes human IL-1ra in ELISA.
Alternate Names: Interleukin-1 receptor antagonist protein, IL-1ra, IRAP, IL1 inhibitor, IL-1RN, ICIL-1RA, Anakinra, IL1RN, IL1F3, IL1RA
Application Notes: E: 1 mg/ml; WB: 1:100-1:1,000
Accession No.: P18510, NP_776214
Antigen: Recombinant human IL1 receptor antagonist protein
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.1% gelatin with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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