CD217 (IL17RA) polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS70755
Background:
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alternative Name:
Interleukin-17 receptor A, IL-17 receptor A, IL-17RA, CDw217, CD_antigen: CD217, :IL17RA, IL17R
Application Dilution: WB: 1:1000 - 1:4000
Specificity: IL17RA polyclonal antibody detects endogenous levels of IL17RA protein.
Immunogen:
Recombinant protein of human IL17RA.
MW: ~ 96 kDa
Swis Prot.: Q96F46
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alternative Name:
Interleukin-17 receptor A, IL-17 receptor A, IL-17RA, CDw217, CD_antigen: CD217, :IL17RA, IL17R
Application Dilution: WB: 1:1000 - 1:4000
Specificity: IL17RA polyclonal antibody detects endogenous levels of IL17RA protein.
Immunogen:
Recombinant protein of human IL17RA.
MW: ~ 96 kDa
Swis Prot.: Q96F46
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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