IL18BP (clone ), anti-human
€388.00
In stock
SKU
MB0143
Background:
The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine,IL18. It binds IL18,prevents the binding of IL18 to its receptor,and thus inhibits IL18-induced IFN-gamma production,resulting in reduced T-helper type 1 immune responses.This protein is constitutively expressed and secreted in mononuclear cells.Elevated level of this protein is detected in the intestinal tissues of patients with Crohn´s disease.Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alternative Name:
IL18 binding protein, IL-18BP, IL18 BP, IL18 BPa, IL18BP, IL18BPa, Interleukin 18 binding protein, Interleukin-18-binding protein, MC51L 53L 54L homolog gene product, Tadekinig alfa, Tadekinig-alfa.
Application Dilution: WB: 1:400~1000
Specificity: This antibody detects endogenous levels of IL18BP and does not cross-react with related proteins
Immunogen:
Recombinant full length Human IL18BP.
MW: Predicted band size: 37KDa, Observed band size: 37/40KDa
Swis Prot.: O95998
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine,IL18. It binds IL18,prevents the binding of IL18 to its receptor,and thus inhibits IL18-induced IFN-gamma production,resulting in reduced T-helper type 1 immune responses.This protein is constitutively expressed and secreted in mononuclear cells.Elevated level of this protein is detected in the intestinal tissues of patients with Crohn´s disease.Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alternative Name:
IL18 binding protein, IL-18BP, IL18 BP, IL18 BPa, IL18BP, IL18BPa, Interleukin 18 binding protein, Interleukin-18-binding protein, MC51L 53L 54L homolog gene product, Tadekinig alfa, Tadekinig-alfa.
Application Dilution: WB: 1:400~1000
Specificity: This antibody detects endogenous levels of IL18BP and does not cross-react with related proteins
Immunogen:
Recombinant full length Human IL18BP.
MW: Predicted band size: 37KDa, Observed band size: 37/40KDa
Swis Prot.: O95998
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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