ING1 polyclonal, anti-human, mouse, rat

Protein Family: Transcription Factors

Pathway and Disease: Transcription, Cancers, Cell Growth and Death

Description:
Inhibitor of growth protein 1 (ING1) cooperates with p53/TP53 in the negative regulatory pathway of cell growth by modulating p53-dependent transcriptional activation. ING1 is implicated as a tumor suppressor gene. Defects in ING1 are a cause of head and neck squamous cell carcinomas (HNSCC), also known as squamous cell carcinoma of the head and neck.

Alternate Names: ING1, Inhibitor of growth protein 1

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: Q9UK53

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ING1.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.