Insulin polyclonal, anti-human, mouse, rat
€378.00
In stock
SKU
250720
Catalog Nr.: 250720
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Protein Family: Hormones
Pathway and Disease: Cancers, Carbohydrate Metabolism, Cell Motility, Endocrine System, Folding, Sorting and Degradation, Lipid Metabolism, Metabolic Disorders, Neurodegenerative Disorders, Signal Transduction
Description:
Insulin is a pancreatic hormone that regulates glucose and is involved in the synthesis of proteins and fat. Insulin increases cell permeability to monosaccharides, amino acids, and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. Insulin is a heterodimer of a B chain and A chain linked by two disulfide bonds. Defects in Insulin are the cause of familial hyperproinsulinemia. Insulin is available under brand names Humulin or Humalog (Eli Lilly) and Novolin (Novo Nordisk) when used for the treatment of diabetes.
Alternate Names: Insulin, Insulin-1, Insulin-1 B chain, Insulin-1 A chain, INS, Ins1, Ins-1
Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500
Accession No.: P01325
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of mouse Insulin.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Zhang T. et al. 2010 Endocrinology. 151(50:2030-2036. PMID# 20215568.
Pathway and Disease: Cancers, Carbohydrate Metabolism, Cell Motility, Endocrine System, Folding, Sorting and Degradation, Lipid Metabolism, Metabolic Disorders, Neurodegenerative Disorders, Signal Transduction
Description:
Insulin is a pancreatic hormone that regulates glucose and is involved in the synthesis of proteins and fat. Insulin increases cell permeability to monosaccharides, amino acids, and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. Insulin is a heterodimer of a B chain and A chain linked by two disulfide bonds. Defects in Insulin are the cause of familial hyperproinsulinemia. Insulin is available under brand names Humulin or Humalog (Eli Lilly) and Novolin (Novo Nordisk) when used for the treatment of diabetes.
Alternate Names: Insulin, Insulin-1, Insulin-1 B chain, Insulin-1 A chain, INS, Ins1, Ins-1
Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500
Accession No.: P01325
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of mouse Insulin.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Zhang T. et al. 2010 Endocrinology. 151(50:2030-2036. PMID# 20215568.
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