IQGAP1 polyclonal, anti-human, mouse, rat

Protein Family: Cytoskeleton Proteins

Pathway and Disease: Cell Communication, Cell Motility

Description:
Ras GTPase-activating-like protein IQGAP1 (IQGAP1) binds to activated CDC42 but does not stimulate its GTPase activity. IQGAP1 associates with calmodulin and plays a role in the reorganization of the actin cytoskeleton at the plasma membrane. IQGAP1 promotes also neurite outgrowth.

Alternate Names: IQGAP1, Ras GTPase-activating-like protein IQGAP1, p195, KIAA0051

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IP: 1:100-1:500

Accession No.: P46940

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human IQGAP1.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.