ISL1 (clone 1B1), anti-human
€394.00
In stock
SKU
252885
Catalog Nr.: 252885
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: WB, IF
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: WB, IF
Protein Family: Transcription Factors
Pathway and Disease: Nervous and Sensory Systems
Description:
ISL1 (ISL1 transcription factor) is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry. Mutations in this gene have been associated with maturity-onset diabetes of the young.
Alternate Names: Insulin gene enhancer protein ISL-1, Islet-1, ISL1
Application Notes: WB: 1:500-1:2000; IF: 1:200-1:1000
Accession No.: P61371
Antigen: Purified recombinant fragment of human ISL1 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Nervous and Sensory Systems
Description:
ISL1 (ISL1 transcription factor) is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry. Mutations in this gene have been associated with maturity-onset diabetes of the young.
Alternate Names: Insulin gene enhancer protein ISL-1, Islet-1, ISL1
Application Notes: WB: 1:500-1:2000; IF: 1:200-1:1000
Accession No.: P61371
Antigen: Purified recombinant fragment of human ISL1 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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