Kif5B-1 Antibody (Central) Blocking Peptide
€363.00
In stock
SKU
AC-BP8170c
Background:
Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. It is composed of an oligomer consisting of two heavy chains and two light chains. Kinesin, which is thought to interact with GRIP1, possesses three structural domains: a large globular N-terminal domain which is responsible for the motor activity of kinesin (it hydrolyzes ATP and binds microtubule), a central alpha-helical coiled coil domain that mediates the heavy chain dimerization; and a small globular C-terminal domain which interacts with other proteins (such as the kinesin light chains), vesicles and membranous organelles. Kinesin is found in newborn and adult brain, liver, kidney, spleen, heart, lung and sciatic nerve.
Other Names:
Kinesin-1 heavy chain, Conventional kinesin heavy chain, Ubiquitous kinesin heavy chain, UKHC, KIF5B, KNS, KNS1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8170c was selected from the Central region of human Kif5B-1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: KIF5B (HGNC:6324)
Gene ID: 3799
Primary Accession: P33176
Other Accession: NP_004512
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. It is composed of an oligomer consisting of two heavy chains and two light chains. Kinesin, which is thought to interact with GRIP1, possesses three structural domains: a large globular N-terminal domain which is responsible for the motor activity of kinesin (it hydrolyzes ATP and binds microtubule), a central alpha-helical coiled coil domain that mediates the heavy chain dimerization; and a small globular C-terminal domain which interacts with other proteins (such as the kinesin light chains), vesicles and membranous organelles. Kinesin is found in newborn and adult brain, liver, kidney, spleen, heart, lung and sciatic nerve.
Other Names:
Kinesin-1 heavy chain, Conventional kinesin heavy chain, Ubiquitous kinesin heavy chain, UKHC, KIF5B, KNS, KNS1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8170c was selected from the Central region of human Kif5B-1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: KIF5B (HGNC:6324)
Gene ID: 3799
Primary Accession: P33176
Other Accession: NP_004512
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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