CD158f1 (KIR2DL5A) polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60608
Background:
NKAT (NK-associated transcripts) gene products, known as killer immunoglobulin-like receptors or KIRs, downregulate the cytotoxicity of NK cells upon recognition of specific class I major histocompatibility complex (MHC) molecules on target cells. This family of receptors is characterized by an extracellular region with two to three immunoglobulin superfamily domains and a cytoplasmic domain with an antigen receptor activation motif (ARAM). KIRs and other inhibitory receptors also possess a common cytoplasmic sequence (I/VxYxxL/V) known as an ITIM (immunoreceptor tyrosine-based inhibitory motif).
Alternative Name:
Killer cell immunoglobulin-like receptor 2DL5A, CD158f1, KIR2DL5A, CD158F, CD158F1, KIR2DL5
Application Dilution: WB: 1:500~1:1000
Specificity: KIR2DL5A polyclonal antibody detects endogenous levels of KIR2DL5A protein.
Immunogen:
A synthetic peptide corresponding to residues in Human KIR2DL5A
MW: ~ 41 kDa
Swis Prot.: Q8N109
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
NKAT (NK-associated transcripts) gene products, known as killer immunoglobulin-like receptors or KIRs, downregulate the cytotoxicity of NK cells upon recognition of specific class I major histocompatibility complex (MHC) molecules on target cells. This family of receptors is characterized by an extracellular region with two to three immunoglobulin superfamily domains and a cytoplasmic domain with an antigen receptor activation motif (ARAM). KIRs and other inhibitory receptors also possess a common cytoplasmic sequence (I/VxYxxL/V) known as an ITIM (immunoreceptor tyrosine-based inhibitory motif).
Alternative Name:
Killer cell immunoglobulin-like receptor 2DL5A, CD158f1, KIR2DL5A, CD158F, CD158F1, KIR2DL5
Application Dilution: WB: 1:500~1:1000
Specificity: KIR2DL5A polyclonal antibody detects endogenous levels of KIR2DL5A protein.
Immunogen:
A synthetic peptide corresponding to residues in Human KIR2DL5A
MW: ~ 41 kDa
Swis Prot.: Q8N109
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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