KLF8 polyclonal, anti-human
€362.00
In stock
SKU
252109
Catalog Nr.: 252109
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB
Protein Family: Transcription Factors
Pathway and Disease: Transcription, Cell Growth and Death
Description:
Krueppel-like factor 8 (KLF8) is a transcriptional repressor and activator. KLF8 binds to CACCC-boxes promoter elements. KLF8 also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G1 phase as a downstream target of focal adhesion kinase (FAK). Sumoylation at Lys-67 represses transcriptional activity and reduces cell cycle progression into the G1 phase.
Alternate Names: Krueppel-like factor 8, Basic krueppel-like factor 3, Zinc finger protein 741, KLF8, BKLF3, ZNF741
Application Notes: E: 1:10,000-1:50,000; WB: 1:200-1:1,000
Accession No.: O95600
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human KLF8.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Wang J et al. 2015. Oncol Lett. 9(6): 2515-9. PMID 26137099.
Pathway and Disease: Transcription, Cell Growth and Death
Description:
Krueppel-like factor 8 (KLF8) is a transcriptional repressor and activator. KLF8 binds to CACCC-boxes promoter elements. KLF8 also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G1 phase as a downstream target of focal adhesion kinase (FAK). Sumoylation at Lys-67 represses transcriptional activity and reduces cell cycle progression into the G1 phase.
Alternate Names: Krueppel-like factor 8, Basic krueppel-like factor 3, Zinc finger protein 741, KLF8, BKLF3, ZNF741
Application Notes: E: 1:10,000-1:50,000; WB: 1:200-1:1,000
Accession No.: O95600
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human KLF8.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Wang J et al. 2015. Oncol Lett. 9(6): 2515-9. PMID 26137099.
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