(KO Validated) DNAJB1 Polyclonal Antibody

Background:
This gene encodes a member of the DnaJ or Hsp40 (heat shock protein 40 kD) family of proteins. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. The encoded protein is a molecular chaperone that stimulates the ATPase activity of Hsp70 heat-shock proteins in order to promote protein folding and prevent misfolded protein aggregation. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Signal Transduction

Synonyms:
DNAJB1, HSPF1, Hdj1, Hsp40, RSPH16B, Sis1

Immunogen: Recombinant fusion protein of human DNAJB1 (NP_006136.1).

Swissprot: P25685
Gene ID: 3337

Calculated MW: 27 kDa/38 kDa
Observed MW: 39 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.