(KO Validated) EGFR Polyclonal Antibody

Background:
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

Research Area: Cancer, Signal Transduction

Synonyms:
EGFR, ERBB, ERBB1, HER1, NISBD2, PIG61, mENA

Immunogen: A synthetic peptide of human EGFR (NP_005219.2).

Swissprot: P00533
Gene ID: 1956

Calculated MW: 44 kDa/69 kDa/77 kDa/134 kDa
Observed MW: 175 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:1000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.