(KO Validated) EZH2 Polyclonal Antibody

Background:
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
ENX-1, ENX1, EZH1, EZH2b, KMT6, KMT6A, WVS, WVS2, EZH2, KMT6 / EZH2

Immunogen: Recombinant fusion protein of human EZH2 (NP_001190176.1).

Swissprot: Q15910
Gene ID: 2146

Calculated MW: 79 kDa/81 kDa/84 kDa/85 kDa/86 kDa
Observed MW: 78-110 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.