(KO Validated) GSS Polyclonal Antibody

Background:
Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.

Research Area: Cancer, Cell Biology, Metabolism, Neuroscience, Signal Transduction

Synonyms:
GSS, GSHS, HEL-S-64p, HEL-S-88n

Immunogen: Recombinant fusion protein of human GSS (NP_000169.1).

Swissprot: P48637
Gene ID: 2937

Calculated MW: 40 kDa/52 kDa
Observed MW: 54 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.