(KO Validated) HPRT1 Polyclonal Antibody

Background:
The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Synonyms:
HPRT1, HGPRT, HPRT

Immunogen: Recombinant fusion protein of human HPRT1 (NP_000185.1).

Swissprot: P00492
Gene ID: 3251

Calculated MW: 24 kDa
Observed MW: 27 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:10-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.