(KO Validated) PARK7 Polyclonal Antibody

Background:
The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Neuroscience, Signal Transduction

Synonyms:
DJ-1, DJ1, GATD2, HEL-S-67p, PARK7

Immunogen: Recombinant fusion protein of human PARK7 (NP_001116849.1).

Swissprot: Q99497
Gene ID: 11315

Calculated MW: 19 kDa
Observed MW: 20 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.